Description
FAT4 Antibody [AMM02551G] | Gentaur UK, US & Europe Distribution
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This FAT4 antibody is generated from a mouse immunized with a recombinant protein between 4500-4786 amino acids from human FAT4.
Cellular Localisation: Membrane; Single-pass type I membrane protein. Note=In the kidney, localizes to primary cilia.
Molecular Weight: 542687
Clone: Monoclonal
Gene Name: FAT4
Gene ID: 79633
Function: Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity) .
Summary: Tissue Location: Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer.
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Protocadherin Fat 4, hFat4, Cadherin family member 14, FAT tumor suppressor homolog 4, Fat-like cadherin protein FAT-J, FAT4, CDHF14, FATJ