FBXL18 polyclonal Antibody | BS9962M

FBXL18 polyclonal Antibody | BS9962M | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC FC

Application Range: WB: 1:500 IHC: 1:50-1:200 FC: 1:50-1:100

Background: FBL18 (F-box and leucine-rich repeat protein 18), also known as FBXL18, is an 805 amino acid protein that contains an F-box near its N-terminus, followed by several leucine-rich repeats and a transmembrane domain at the C-terminus. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins and cyclin-dependent kinase inhibitors (CDKNs), for degradation by the proteasome after ubiquitination.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of FBXL18 and does not cross-react with related proteins.

Molecular Weight: ~ 40, 88 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: F-box/LRR-repeat protein 18; F-box and leucine-rich repeat protein 18; FBXL18; FBL18

Immunogen: Synthetic peptide corresponding to human FBXL18 aa 750 to C terminus.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A affinity purified.

Pathway: Glutamine Metabolism,