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FBXO22 polyclonal Antibody | BS71188
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- BW-BS71188
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Description
FBXO22 polyclonal Antibody | BS71188 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB
Application Range: WB 1:500 - 1:2000
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FBXO22 polyclonal Antibody detects endogenous levels of FBXO22 protein.
Molecular Weight: ~ 45 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FBX22; FISTC1;
Immunogen: Recombinant protein of human FBXO22.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: