Fc epsilon Receptor I alpha Antibody [FceR1] | 77-175

Fc epsilon Receptor I alpha Antibody [FceR1] | 77-175 | Gentaur UK, US & Europe Distribution

Host: Hamster

Reactivity: Mouse

Homology: N/A

Immunogen: N/A

Research Area: Innate Immunity

Tested Application: Flow, Func, IHC, IP

Application: N/A

Specificiy: The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa) , a transmembrane protein member of the Ig superfamily.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Clonality: Monoclonal

Clone: FceR1

Isotype: Armenian Hamster IgG

Conjugate: Unconjugated

Physical State: liquid

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Concentration: batch dependent

Storage Condition: The product should be stored undiluted at 4˚C . Do not freeze.

Alternate Name: FCE1A, FcER, FCER1A

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa) , a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo.