Fc epsilon Receptor I alpha Antibody [FceR1] (FITC) | 77-177

Fc epsilon Receptor I alpha Antibody [FceR1] (FITC) | 77-177 | Gentaur UK, US & Europe Distribution

Host: Hamster

Reactivity: Mouse

Homology: N/A

Immunogen: N/A

Research Area: Innate Immunity

Tested Application: Flow

Application: N/A

Specificiy: The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a) , which is a transmembrane glycoprotein from the immunoglobulin superfamily.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clonality: Monoclonal

Clone: FceR1

Isotype: Armenian Hamster IgG

Conjugate: FITC

Physical State: liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Concentration: batch dependent

Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.

Alternate Name: FCE1A, FcER, FCER1A

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a) , which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc epsilon Receptor I alpha subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs) . The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.