FCHSD1 Antibody | 6509

FCHSD1 Antibody | 6509 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Mouse

Homology: N/A

Immunogen: FCHSD1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human FCHSD1.
The immunogen is located within the last 50 amino acids of FCHSD1.

Research Area: Neuroscience

Tested Application: E, WB

Application: FCHSD1 antibody can be used for detection of FCHSD1 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: Multiple isoforms of FCHSD1 are known to exist. FCHSD1 antibody is predicted to not cross-react with FCHSD2

Positive Control 1: Cat. No. 1219 - MCF7 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 76 kDa
Observed: 82 kDa

Validation: N/A

Isoform: N/A

Purification: FCHSD1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgY

Conjugate: Unconjugated

Physical State: Liquid

Buffer: FCHSD1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: FCHSD1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: FCHSD1 Antibody: NWK2, FCH and double SH3 domains protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FCHSD1 Antibody: The FCH and double SH3 domains protein 1 (FCHSD1, also known as NWK2) and the related protein FCHSD2 were initially identified in silico as distantly related proteins to FNBP1 and FNBP2. Both share the common domain structure consisting of FCH, FBH, two SH3 and C-terminal proline-rich domains. While little is known of the function of FCHSD1, the related protein NWK is an adaptor protein that is thought to regulate Rho activity downstream of Robo receptors, suggesting that FCHSD1 may be involved in synaptic morphology by regulating actin dynamics in presynaptic terminals.