FCN1 Polyclonal Antibody | E-AB-40113

FCN1 Polyclonal Antibody | E-AB-40113 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Collagen/fibrinogen domain containing protein 1, Collagen/fibrinogen domain-containing protein 1, Fcn1, FCN1, FCNM, ficolin (collagen/fibrinogen domain containing) 1, Ficolin 1, Ficolin A, Ficolin alpha, Ficolin-1, Ficolin-A, Ficolin-alpha, M ficolin, M-ficolin

Application: IHC

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Immunology

Background: Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant human Ficolin-1 protein

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: IHC 1:50-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A