FGF-6, human recombinant | 7148

FGF-6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. Recombinant human FGF-6 is an 18.7 kDa protein consisting of 168 amino acid residues.

7148 | FGF-6 human recombinant DataSheet

Biomolecule/Target: FGF-6

Synonyms: Fibroblast Growth Factor-6, HBGF-6, HST-2

Alternates names: Resistin-like , RELM , Cysteine-rich secreted protein FIZZ2, Colon and small intestine-specific cysteine-rich protein, Cysteine-rich secreted protein A12--like 1, Colon carcinoma-related gene protein, RELM-b, XCP2, HXCP2

Taglines: Promotes cellular proliferation and differentiation

NCBI Gene ID #: 84666

NCBI Gene Symbol: RETNB

Gene Source: Human

Accession #: Q9BQ08

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by the dose dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is 0.5 ng/ml corresponding to a specific activity of 2 x 10^6 units/mg.

Biological activity: Test in process

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 11.0 kDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Tris, pH 7.5, and 50 mM NaCl.

Reconstitution Instructions: Reconstitute to 1 mg/ml with sterilized dHO. Pipet to dissolve the protein pellet completely.

Amino acid sequence: N/A