FGF-basic 147, human recombinant | 4036

Fibroblast Growth Factors, FGFs, are a 22 member family of proteins known to be involved in angiogenesis, wound healing and embryonic development. As a family, they bind to heparin and signal through four receptor tyrosine kinases called, FGFR1, 2, 3 and 4. Although the mechanism remains unclear, FGF-basic 147 (variant of FGF basic 154) is a critical component in keeping embryonic stem cells undifferentiated in cell culture systems. Recombinant human FGF-b 147 (FGF-2) is a non-glycosylated protein, containing 147 amino acids, and having a molecular mass of 16.5 kDa.

4036 | FGF-basic 147 human recombinant DataSheet

Biomolecule/Target: FGF-basic 147

Synonyms: FGFB

Alternates names: Gremlin-2, Cysteine knot superfamily 1, BMP antagonist 2, Protein related to DAN and cerberus, DAN domain family member 3

Taglines: A growth factor involved in angiogenesis, wound healing and embryonic development

NCBI Gene ID #: 64388

NCBI Gene Symbol: GREM2

Gene Source: Human

Accession #: Q9H772

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: <0.01 ng/g

Activity (Specifications/test method): N/A

Biological activity: Test in process

Results: 0.67-1.45 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 17.2 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from a 10 mM Na2PO4, pH 8.0.

Reconstitution Instructions: Reconstitute to 1 mg/ml with sterilized dHO. Pipette to dissolve the protein pellet completely

Amino acid sequence: N/A