FGFR1/2 (phospho Tyr463/466) Antibody | 79-883

FGFR1/2 (phospho Tyr463/466) Antibody | 79-883 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: FGFR1/2 (phospho Tyr463/466) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p) -E-L) derived from Human FGFR1/2.

Research Area: Phospho-Specific

Tested Application: WB

Application: N/A

Specificiy: The antibody detects endogenous levels of FGFR1/2 only when phosphorylated at tyrosine 463/466.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 91 kDa

Validation: N/A

Isoform: N/A

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/mL

Storage Condition: Store antibody at -20˚C for up to one year.

Alternate Name: BFGFR, CEK, FLG, CD331, FLT2

User Note: N/A

BACKGROUND: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.