FGG monoclonal Antibody | MB63299

FGG monoclonal Antibody | MB63299 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse

Application: IHC, WB

Application Range: WB 1:400~4000, IHC 1:150

Background: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: fibrinogen gamma chain

Molecular Weight: 46.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide

Immunogen: Full length human recombinant protein of human FGG (NP_000500) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A