Fibrinogen polyclonal Antibody | BS90512

Fibrinogen polyclonal Antibody | BS90512 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB ICC FC

Application Range: WB:1:500 ICC:1:100-1:500 FC:1:50-1:100

Background: The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Fibrinogen polyclonal Antibody detects endogenous levels of Fibrinogen protein.

Molecular Weight: 70/55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FGA, FGB, FGG, FGA, Fib2, FIBA, Fibrinogen A alpha polypeptide, Fibrinogen alpha chain, Fibrinogen B alpha polypeptide, Fibrinogen beta chain, Fibrinogen G alpha polypeptide, Fibrinogen gamma chain, fibrinogen, B beta polypeptide, fibrinogen, G gamma polypeptide, fibrinogen, gamma polypeptide, Fibrinogenalpha -polypeptide chain, Fibrinogenbeta -polypeptide chain, Fibrinogengamma-polypeptide chain,

Immunogen: Native protein.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: