Fibulin 5 polyclonal Antibody | BS90515

Fibulin 5 polyclonal Antibody | BS90515 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:1,000-1:2,000 ICC:1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: Fibulin proteins contribute to normal development of elastic fiber systems in various types of organs that require elasticity, such as vasculature, lung and skin. Fibulin-5 (EVEC, UP50, DANCE) is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion. Fibulin-5 is also a calcium-dependent elastin-binding protein that scaffolds cells to elastic fibers, thereby preventing elastinopathy in the skin, lung, and vasculature. The Arg-Gly-Asp (RGD) motif in Fibulin-5 interacts with cell surface integrins avb3, avb5 and a9b1, serves as an anchorage for elastic fibers to cells, and promotes organization of elastic fibers. The human Fibulin-5 gene maps to chromosome 14q32.12 and encodes a 488 amino acid protein.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: Fibulin 5 polyclonal Antibody detects endogenous levels of Fibulin 5 protein.

Molecular Weight: 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FIBL-5, Dance, UP50, FBLN5, DANCE, ADCL2, ARCL1A, ARMD3, Dance, Developmental arteries and neural crest EGF like protein, Developmental arteries and neural crest EGF-like protein, EVEC, Fbln5, FBLN5, FIBL 5, FIBL-5, Fibulin-5, FLJ90059, UP50, Urine p50 protein,

Immunogen: Recombinant protein within human Fibulin 5 210-360 aa.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: