Additional Information
Size:  | 
                                                    100 µg  | 
                                                
Target:  | 
                                                    FIP200  | 
                                                
Conjugate:  | 
                                                    APC/Cy7  | 
                                                
Research Area:  | 
                                                    Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | FAK / PYK | Cell Signaling | Metabolism | Cancer | Autophagy  | 
                                                
Alternative Name:  | 
                                                    RB1CC1 Antibody, FAK family kinase-interacting protein of 200 kDa Antibody, FIP200 Antibody, KIAA0203 Antibody, RBICC Antibody, RB1-inducible coiled-coil protein 1 Antibody  | 
                                                
Category:  | 
                                                    Antibodies  | 
                                                
Product Type:  | 
                                                    Polyclonal Antibody  | 
                                                
Immunogen:  | 
                                                    Synthetic peptide from the C-terminal of Human FIP200 (aa. 1355-1366)  | 
                                                
Immunogen Species:  | 
                                                    Human  | 
                                                
Applications:  | 
                                                    WB, ICC/IF  | 
                                                
Host:  | 
                                                    Rabbit  | 
                                                
Isotype:  | 
                                                    N/A  | 
                                                
Species Reactivity:  | 
                                                    Human, Rat  | 
                                                
Antibody Dilution:  | 
                                                    WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.  | 
                                                
Purification:  | 
                                                    Peptide Affinity Purified  | 
                                                
Storage Buffer:  | 
                                                    PBS, 50% glycerol, 0.09% sodium azide  | 
                                                
Concentration:  | 
                                                    1 mg/ml  | 
                                                
Specificity:  | 
                                                    Detects ~150 kDa.  | 
                                                
Storage:  | 
                                                    -20ºC  | 
                                                
Shipping:  | 
                                                    Blue Ice or 4ºC  | 
                                                
Certificate of Analysis:  | 
                                                    A 1:1000 dilution of SPC-658 was sufficient for detection of FIP200 in 15 µg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.  | 
                                                
Cellular Localization:  | 
                                                    Nucleus, Cytoplasm, Cytoplasm, Cytosol, Preautophagosomal Structure  | 
                                                
Tissue Specificity:  | 
                                                    Expression levels correlated closely with those of RB1 in cancer cell lines as well as in various normal human tissues. Abundantly expressed in human musculoskeletal and cultured osteosarcoma cells.  | 
                                                
Accession Number:  | 
                                                    NP_001077086.1  | 
                                                
Gene ID:  | 
                                                    9821  | 
                                                
Swiss-Prot:  | 
                                                    Q8TDY2  | 
                                                
Field of Use:  | 
                                                    For in vitro research use only.  |