Description
FITC Anti-Mouse CD62L Antibody[Mel14] | E-AB-F1011UC | Gentaur UK, US & Europe Distribution
Category: Flowcytometry Antibody
Synonyms: L-selectin,Sell,CD62 antigen-like family member L,LAM-1,LECAM1,Lymph node homing receptor,Ly-22, CD62L,Lnhr,Ly22
Swissprot Code: P18337
Application: FCM
Reactivity: Human
Host: Mouse
Isotype: Mouse IgG1, κ
Research Areas: Cancer, Cardiovascular, Immunology, Stem cells
Backgroun: CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and nave T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish nave, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.
Concentration: 0.5 mg/mL
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Buffer: PBS with 0.05% Proclin300, 1% BSA
Purification Method: N/A
Dilution: N/A
Clone: Mel14
Conjugation: FITC
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A