FITC-DEVD-FMK | 9499

FITC-D(OMe)E(OMe)VD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase inhibitor D(OMe)E(OMe)VD(OMe)-FMK that acts as an in situ marker for detection of caspase-3 in living cells. FITC-D(OMe)E(OMe)VD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-3 in apoptotic cells. The bound marker is localized by fluorescence detection

FITC-D(OMe)E(OMe)VD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase inhibitor D(OMe)E(OMe)VD(OMe)-FMK that acts as an in situ marker for detection of caspase-3 in living cells. FITC-D(OMe)E(OMe)VD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-3 in apoptotic cells. The bound marker is localized by fluorescence detection

9499 | FITC-DEVD-FMK DataSheet

Alternate Name/Synonyms: FITC-Asp-Glu-Val-Asp-fluoromethyl ketone; FITC-D(OMe)-E(OMe)-VD(OMe)-FMK

Appearance: Liquid

Formulation: A 0.6 mM solution in DMSO

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: FITC-D(OMe)-E(OMe)-VD(OMe)-FMK

Salt Form: No

Molecular Formula: C₄₃H₄₆FN₅O₁₅S

Molecular Weight: 923.91

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A caspase-3 in situ marker

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(OC)CC[C@H](NC([C@@H](N/C(S)=N/C1=CC=C(C2(C3=CC=C(O)C=C3OC4=C2C=CC(O)=C4)OC5=O)C5=C1)CC(OC)=O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O

InChi: InChI=1S/C43H46FN5O15S/c1-20(2)37(40(58)47-29(31(52)19-44)17-35(54)61-4)49-38(56)28(12-13-34(53)60-3)46-39(57)30(18-36(55)62-5)48-42(65)45-21-6-9-25-24(14-21)41(59)64-43(25)26-10-7-22(50)15-32(26)63-33-16-23(51)8-11-27(33)43/h6-11,14-16,20,28-30,37,50-51H,12-13,17-19H2,1-5H3,(H,46,57)(H,47,58)(H,49,56)(H2,45,48,65)/t28-,29-,30-,37-/m0/s1

InChi Key: GRXLYHYCYCURGM-OWBZZYPYSA-N