FITC-IETD-FMK | 9533

FITC-IE(OMe)TD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-8 inhibitor IE(OMe)TD(OMe)-FMK that acts as an in situ marker for detection of caspase-8 in living cells. FITC-IE(OMe)TD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-8 in apoptotic cells. The bound marker is localized by fluorescence detection.

FITC-IE(OMe)TD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-8 inhibitor IE(OMe)TD(OMe)-FMK that acts as an in situ marker for detection of caspase-8 in living cells. FITC-IE(OMe)TD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-8 in apoptotic cells. The bound marker is localized by fluorescence detection.

9533 | FITC-IETD-FMK DataSheet

Alternate Name/Synonyms: FITC-Ile-Glu-Thr-Asp-fluoromethyl ketone; FITC-I-E(OMe)-TD(OMe)-FMK

Appearance: Liquid

Formulation: A 0.6 mM solution in DMSO

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: FITC-I-E(OMe)-TD(OMe)-FMK

Salt Form: No

Molecular Formula: C₄₃H₄₈FN₅O₁₄S

Molecular Weight: 909.93

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A caspase-8 in situ marker

MDL Number: N/A

PubChem CID: N/A

SMILES: S/C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O)CCC(OC)=O)=O)=N\C1=CC=C(C2(C3=CC=C(O)C=C3OC4=C2C=CC(O)=C4)OC5=O)C5=C1

InChi: InChI=1S/C43H48FN5O14S/c1-6-20(2)36(39(57)46-29(13-14-34(54)60-4)38(56)48-37(21(3)50)40(58)47-30(31(53)19-44)18-35(55)61-5)49-42(64)45-22-7-10-26-25(15-22)41(59)63-43(26)27-11-8-23(51)16-32(27)62-33-17-24(52)9-12-28(33)43/h7-12,15-17,20-21,29-30,36-37,50-52H,6,13-14,18-19H2,1-5H3,(H,46,57)(H,47,58)(H,48,56)(H2,45,49,64)/t20-,21+,29-,30-,36-,37-/m0/s1

InChi Key: ZQSUFEPGEWYBEF-NINMPSEZSA-N