FITC-LEHD-FMK | 9534

FITC-LE(OMe)HD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-9 inhibitor LE(OMe)HD(OMe)-FMK that acts as an in situ marker for detection of caspase-9 in living cells. FITC-LE(OMe)HD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-9 in apoptotic cells. The bound marker is localized by fluorescence detection.

FITC-LE(OMe)HD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-9 inhibitor LE(OMe)HD(OMe)-FMK that acts as an in situ marker for detection of caspase-9 in living cells. FITC-LE(OMe)HD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-9 in apoptotic cells. The bound marker is localized by fluorescence detection.

9534 | FITC-LEHD-FMK DataSheet

Alternate Name/Synonyms: FITC-Leu-Glu-His-Asp-fluoromethyl ketone; FITC-L-E(OMe)-HD(OMe)-FMK

Appearance: Liquid

Formulation: A 0.6 mM solution in DMSO

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: FITC-L-E(OMe)-HD(OMe)-FMK

Salt Form: No

Molecular Formula: C₄₅H₄₈FN₇O₁₃S

Molecular Weight: 945.97

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A caspase-9 in situ marker

MDL Number: N/A

PubChem CID: N/A

SMILES: S/C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O)CCC(OC)=O)=O)=N\C2=CC=C(C3(C4=CC=C(O)C=C4OC5=C3C=CC(O)=C5)OC6=O)C6=C2

InChi: InChI=1S/C45H48FN7O13S/c1-22(2)13-33(41(60)50-31(11-12-38(57)63-3)40(59)52-34(15-24-20-47-21-48-24)42(61)51-32(35(56)19-46)18-39(58)64-4)53-44(67)49-23-5-8-28-27(14-23)43(62)66-45(28)29-9-6-25(54)16-36(29)65-37-17-26(55)7-10-30(37)45/h5-10,14,16-17,20-22,31-34,54-55H,11-13,15,18-19H2,1-4H3,(H,47,48)(H,50,60)(H,51,61)(H,52,59)(H2,49,53,67)/t31-,32-,33-,34-/m0/s1

InChi Key: QDHULOWFRSEJMR-CUPIEXAXSA-N