FITC-VAD-FMK | 9497

FITC-VAD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable pan-caspase inhibitor VAD(OMe)-FMK that acts as an in situ marker for detection of caspase in living cells. FITC-VAD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase in apoptotic cells. The bound marker is localized by fluorescence detection.

FITC-VAD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable pan-caspase inhibitor VAD(OMe)-FMK that acts as an in situ marker for detection of caspase in living cells. FITC-VAD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase in apoptotic cells. The bound marker is localized by fluorescence detection.

9497 | FITC-VAD-FMK DataSheet

Alternate Name/Synonyms: FITC-Val-Ala-Asp- fluoromethyl ketone; FITC-VAD(OMe)-FMK

Appearance: Liquid

Formulation: A 0.6 mM solution in DMSO

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: FITC-VAD(OMe)-FMK

Salt Form: No

Molecular Formula: C₃₅H₃₅FN₄O₁₀S

Molecular Weight: 722.74

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A pan-caspase in situ marker

MDL Number: N/A

PubChem CID: N/A

SMILES: S/C(NC(C(C)C)C(NC(C)C(NC(C(CF)=O)CC(OC)=O)=O)=O)=N\C1=CC=C(C2(C3=CC=C(O)C=C3OC4=C2C=CC(O)=C4)OC5=O)C5=C1

InChi: InChI=1S/C35H35FN4O10S/c1-16(2)30(32(46)37-17(3)31(45)39-25(26(43)15-36)14-29(44)48-4)40-34(51)38-18-5-8-22-21(11-18)33(47)50-35(22)23-9-6-19(41)12-27(23)49-28-13-20(42)7-10-24(28)35/h5-13,16-17,25,30,41-42H,14-15H2,1-4H3,(H,37,46)(H,39,45)(H2,38,40,51)

InChi Key: HTVXQJAJPCZKBH-UHFFFAOYSA-N