FITC-VDVAD-FMK | 9498

FITC-VD(OMe)VAD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-2 inhibitor VD(OMe)VAD(OMe)-FMK that acts as an in situ marker for detection of caspase-2 in living cells. FITC-VD(OMe)VAD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-2 in apoptotic cells. The bound marker is localized by fluorescence detection.

FITC-VD(OMe)VAD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-2 inhibitor VD(OMe)VAD(OMe)-FMK that acts as an in situ marker for detection of caspase-2 in living cells. FITC-VD(OMe)VAD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-2 in apoptotic cells. The bound marker is localized by fluorescence detection.

9498 | FITC-VDVAD-FMK DataSheet

Alternate Name/Synonyms: FITC-Val-Asp-Val-Ala-Asp-fluoromethyl ketone; FITC-VD(OMe)-VAD(OMe)-FMK

Appearance: Liquid

Formulation: A 0.6 mM solution in DMSO

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: FITC-VD(OMe)-VAD(OMe)-FMK

Salt Form: No

Molecular Formula: C₄₅H₅₁FN₆O₁₄S

Molecular Weight: 950.98

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A caspase-2 in situ marker

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(OC)C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N/C(S)=N/C1=CC=C(C2(C3=CC=C(O)C=C3OC4=C2C=CC(O)=C4)OC5=O)C5=C1)C(C)C)=O)CC(OC)=O)=O)C(C)C)=O)C)=O)C(CF)=O

InChi: InChI=1S/C45H51FN6O14S/c1-20(2)37(41(60)47-22(5)39(58)49-30(32(55)19-46)17-35(56)63-6)51-40(59)31(18-36(57)64-7)50-42(61)38(21(3)4)52-44(67)48-23-8-11-27-26(14-23)43(62)66-45(27)28-12-9-24(53)15-33(28)65-34-16-25(54)10-13-29(34)45/h8-16,20-22,30-31,37-38,53-54H,17-19H2,1-7H3,(H,47,60)(H,49,58)(H,50,61)(H,51,59)(H2,48,52,67)/t22-,30-,31-,37-,38-/m0/s1

InChi Key: UDNJMPACZZTQQK-MZPOKIFTSA-N