FKBP5 polyclonal Antibody | BS72339

FKBP5 polyclonal Antibody | BS72339 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FKBP5 polyclonal Antibody detects endogenous levels of FKBP5 protein.

Molecular Weight: ~ 51 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AIG6;FKBP51;FKBP54;P54;PPIase;Ptg-10

Immunogen: Recombinant protein of human FKBP5

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Histone Lysine Methylation Pathway,Examples of Crosstalk Between Post-translational Modifications,DNA Methylation,