Flucytosine | B3299

Flucytosine, a fluorinated pyrimidine analog that displays antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. Flucytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.

Flucytosine, a fluorinated pyrimidine analog that displays antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. Flucytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.

B3299 | Flucytosine DataSheet

Alternate Name/Synonyms: NSC 103805 5-Fluorocytosine 6-amino-5-fluoro-2(1H)-pyrimidinone 5-FC

Appearance: White to off-white solid

Formulation:

CAS Number: 2022-85-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄H₄FN₃O

Molecular Weight: 129.09

Cell-Permeable?: TRUE

Purity: ≥98% by HPLC

Solubilities: ~0.2 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A cytotoxic drug

MDL Number: MFCD00006035

PubChem CID: 3366

SMILES: C1=NC(=O)NC(=C1F)N

InChi: InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)

InChi Key: XRECTZIEBJDKEO-UHFFFAOYSA-N