Fibrinogen is a glycoprotein complex composed of three different polypeptides (?, ?, ?) that is cleaved by thrombin to form an insoluble fibrin matrix that acts as a plasma clotting factor. Cleavage...
A potent and selective CRTh2 antagonist. CRTh2 is a G-protein-coupled receptor for prostaglandin D2 (PGD2), a key mediator in inflammatory disorders.ACT-129968 is a potent and selective CRTh2...