FMR1 (FMRP ) monoclonal Antibody | MB63313

FMR1 (FMRP ) monoclonal Antibody | MB63313 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat, Dog

Application: IHC, WB

Application Range: WB 1:200~1000, IHC 1:150

Background: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1) . Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: fragile X mental retardation 1

Molecular Weight: 71 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FMRP; FRAXA; POF; POF1; POFX

Immunogen: Human recombinant protein fragment corresponding to amino acids 26-279 of human FMR1 (NP_002015) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A