FN3K Antibody (N-term) (Ascites) [AMM04559G]

FN3K Antibody (N-term) (Ascites) [AMM04559G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: Purified His-tagged FN3K protein was used to produced this monoclonal antibody.

Cellular Localisation: N/A

Molecular Weight: 35171

Clone: Monoclonal

Gene Name: FN3K {ECO:0000303|PubMed:14633848, ECO:0000312|HGNC:HGNC:24822}

Gene ID: 64122

Function: Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate (PubMed:11016445, PubMed:11522682, PubMed:11975663) . Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions (PubMed:11522682, PubMed:11975663) . Involved in intracellular deglycation in erythrocytes (PubMed:11975663) . Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function (By similarity) . Also able to phosphorylate psicosamines and ribulosamines (PubMed:14633848) .

Summary: Tissue Location: Widely expressed (PubMed:11522682) . Expressed in erythrocytes (PubMed:11016445) .

Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000~8000

Synonyms: Fructosamine-3-kinase, 271-, FN3K