FNTB polyclonal Antibody | BS90522

FNTB polyclonal Antibody | BS90522 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Application: WB ICC/IF

Application Range: WB:1:1,000-1:2,000 ICC:1:50-1:200

Background: Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical α and β subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The β subunit, which is known as FTβ, CAAX farnesyltransferase subunit β, or Ras proteins prenyltransferase subunit β, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The α subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: FNTB polyclonal Antibody detects endogenous levels of FNTB protein.

Molecular Weight: 43 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FTase-beta, FNTB, CAAX farnesyltransferase subunit beta, EC 2.5.1.58, EC=2.5.1.58, Farnesyltransferase, farnesyltransferase CAAX box beta1, farnesyltransferase, CAAX box, beta, FNTB, FNTB, FPTB, FTase beta, FTase-beta, MGC105303, Protein farnesyltransferase subunit beta, RAS proteins prenyltransferase beta, Ras proteins prenyltransferase subunit beta,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: