FOLR2 Antibody [AMM22266G]

FOLR2 Antibody [AMM22266G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This FOLR2 antibody is generated from a mouse immunized with a recombiant protein from human FOLR2.

Cellular Localisation: Cell membrane; Lipid-anchor, GPI-anchor. Secreted

Molecular Weight: 29280

Clone: Monoclonal

Gene Name: FOLR2

Gene ID: 2350

Function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Summary: Tissue Location: Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000-1:2000

Synonyms: Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2