FOLR4 Antibody (N-term) [APR30880G]

FOLR4 Antibody (N-term) [APR30880G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This FOLR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human FOLR4.

Cellular Localisation: Cell membrane {ECO:0000250|UniProtKB:Q9EQF4}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9EQF4}. Note=GPI- anchored at the oolemma. {ECO:0000250|UniProtKB:Q9EQF4}

Molecular Weight: 28672

Clone: Polyclonal

Gene Name: IZUMO1R (HGNC:32565)

Gene ID: 390243

Function: Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Sperm-egg fusion protein Juno, Folate receptor 4, Folate receptor delta, FR-delta, IZUMO1 receptor protein JUNO, IZUMO1R (HGNC:32565), FOLR4, JUNO