FOXC1 Antibody | 18-872

FOXC1 Antibody | 18-872 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 404-553 of human FOXC1 (NP_001444.2) .

Research Area: Cell Cycle, Transcription

Tested Application: WB, IHC

Application: WB: 1:100 - 1:1000
IHC: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: Jurkat

Positive Control 3: SKOV3

Positive Control 4: Mouse kidney

Positive Control 5: Mouse lung

Positive Control 6: Rat brain

Molecular Weight: Observed: 70kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: FOXC1, ARA, IGDA, IHG1, FKHL7, IRID1, RIEG3, FREAC3, FREAC-3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.