FOXO3A (phospho-S253) Rabbit monoclonal Antibody | BS9944M

FOXO3A (phospho-S253) Rabbit monoclonal Antibody | BS9944M | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:1000-1:5000 IHC: 1:50-1:200

Background: FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation.FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of FOXO3A protein only when phosphorylated at Ser253.

Molecular Weight: ~ 71, 97 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1; FOXO3A

Immunogen: Recombinant Antibody.

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: Protein A affinity purified

Pathway: