FoxO4 (P191) polyclonal Antibody | BS3575

FoxO4 (P191) polyclonal Antibody | BS3575 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: IHC:1:50~1:200

Background: FOX4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FoxO4 (P191) polyclonal Antibody detects endogenous levels of FoxO4 protein.

Molecular Weight: ~ 55, 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Forkhead box protein O4; Fork head domain transcription factor AFX1; AFX; AFX1; MLLT7; FOXO4

Immunogen: Synthetic peptide, corresponding to amino acids 172-215 of Human FoxO4.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Phosphoinosotode Signaling,Regulation of Actin Dynamics,Tumor Angiogenesis,Regulation of Microtubule Dynamics,B cell receptor signaling,