FR-α (Y80) polyclonal Antibody | BS3861

FR-α (Y80) polyclonal Antibody | BS3861 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The folate receptors consist of five members, α, β, γ, γ’ (which is produced by alternative splicing) and δ. β-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin. γ-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow. The expression pattern of δ-FR is elusive, which suggests that it is highly restricted both spatially and temporally. The α isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FR-α (Y80) polyclonal Antibody detects endogenous levels of FR-α (Y80) protein.

Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Folate receptor alpha; Folate receptor-α; FRα; FR-alpha; Adult folate-binding protein; FBP; Folate receptor 1; Folate receptor, adult; KB cells FBP; Ovarian tumor-associated antigen MOv18; FOLR1; FOLR

Immunogen: Synthetic peptide, corresponding to amino acids 60-110 of Human FR-α.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A