FSTL1 Antibody (C-term) [APR03448G]

FSTL1 Antibody (C-term) [APR03448G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M, Rat

Specificity: This FSTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-308 amino acids from the C-terminal region of human FSTL1.

Cellular Localisation: Secreted.

Molecular Weight: 34986

Clone: Polyclonal

Gene Name: FSTL1

Gene ID: 11167

Function: Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation (PubMed:29212066, PubMed:22265692) . Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (By similarity) . Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes (By similarity) . Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (PubMed:20054002, PubMed:22265692) .

Summary: Tissue Location: Overexpressed in synovial tissues from rheumatoid arthritis (PubMed:15638044) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000

Synonyms: Follistatin-related protein 1, Follistatin-like protein 1, FSTL1, FRP