FUS Polyclonal Antibody | E-AB-17100

FUS Polyclonal Antibody | E-AB-17100 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 75 kDa DNA pairing protein, 75 kDa DNA-pairing protein, ALS6, Amyotrophic lateral sclerosis 6, fus, FUS CHOP, Fus like protein, FUS, FUS1, Fused in sarcoma, Fusion (involved in t(12;16) in malignant liposarcoma), Fusion derived from t(12;16) malignant liposarcoma, Fusion gene in myxoid liposarcoma, Heterogeneous nuclear ribonucleoprotein P2, hnRNP P2, hnRNPP2, Oncogene FUS, Oncogene TLS, POMp75, RNA binding protein FUS, RNA-binding protein FUS, TLS, TLS CHOP, Translocated in liposarcoma, Translocated in liposarcoma protein

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal transduction

Background: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human FUS

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:30-150, ELISA 1:2000-10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A