FXN / Frataxin Antibody, KO Validated | 16-714

FXN / Frataxin Antibody, KO Validated | 16-714 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-210 of human FXN / Frataxin (NP_000135.2) .

Research Area: Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: K-562

Positive Control 2: U-87MG

Positive Control 3: Jurkat

Positive Control 4: Raji

Positive Control 5: DU-145

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 14kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Frataxin, mitochondrial, Friedreich ataxia protein, Fxn, Frataxin intermediate form, i-FXN, Frataxin (56-210) , m56-FXN, Frataxin (78-210) , d-FXN, m78-FXN, Frataxin mature form, Frataxin (81-210) , m81-FXN, FXN, FRDA, X25

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.