FXR2 (E576) polyclonal Antibody | BS2008

FXR2 (E576) polyclonal Antibody | BS2008 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF IP

Application Range: WB: 1:500~1:1000 IHC/IF: 1:50~1:200 IP: 1:10~1:100

Background: The FMR1 protein (or FMRP) is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle. It contains several features that are characteristics of RNA-binding proteins, including two hnRNPK homology (KH) domains and an RGG amino acid motif (RGG box) . FMR1 can also interact with two fragile X syndrome related factors, FXR1 and FXR2, and these proteins form heterodimers through their N-terminal coilcoiled domains. FMR1 localizes to both the nucleus and the cytoplasm, and since it contains both a nuclear localization signal and a nuclear export signal it is also implicated in the nucleo-cytoplasmic transport of mRNAs.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FXR2 (E576) polyclonal Antibody detects endogenous levels of FXR2 protein.

Molecular Weight: ~ 74 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Fragile X mental retardation syndrome-related protein 2; FMR1L2; FXR2

Immunogen: Synthetic peptide, corresponding to amino acids 550-600 of Human FXR2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: