FXYD2 polyclonal Antibody | BS60253

FXYD2 polyclonal Antibody | BS60253 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA) . FXYD2 ? subunit modulates NKA activity by inducing ion channel activity. The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids. Other members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD3 (Mat8, mammary tumor protein 8), FXYD4 (CHIF) and FXYD5 (RIC) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FXYD2 polyclonal Antibody detects endogenous levels of FXYD2 protein.

Molecular Weight: ~ 7 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Sodium/potassium-transporting ATPase subunit gamma; Na (+) /K (+) ATPase subunit gamma; FXYD domain-containing ion transport; regulator 2; Sodium pump gamma chai; FXYD2; ATP1C, ATP1G1

Immunogen: A synthetic peptide corresponding to residues in Human FXYD2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: