GABARAPL1 polyclonal Antibody | BS70920

GABARAPL1 polyclonal Antibody | BS70920 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: GABARAPL1 (γ-aminobutyric acid receptor-associated protein-like 1), also known as ATG8, GEC1 (glandular epithelial cell protein 1), APG8L, ATG8L or APG8-LIKE, is a 117 amino acid protein belonging to the MAP1 LC3 family. Localized to the endoplasmic reticulum and Golgi apparatus, GABARAPL1 is ubiquitously expressed. Very high levels of GABARAPL1 are found in brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. GABARAPL1 increases cell-surface expression of κ-type opioid receptor (KOR) through facilitating anterograde intracellular trafficking of the receptor. GABARAPL1 may have chaperone-like effects for many cell surface proteins along the biosynthesis pathway and may regulate the trafficking of receptor GABA. GABARAPL1 interacts with GABAA Rγ2, β Tubulin and KOR-1.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GABARAPL1 polyclonal Antibody detects endogenous levels of GABARAPL1 protein.

Molecular Weight: ~ 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ATG8; GEC1; APG8L; ATG8B; ATG8L; APG8-LIKE;

Immunogen: Recombinant protein of human GABARAPL1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: