GABRG2 Antibody | 28-313

GABRG2 Antibody | 28-313 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, Dog

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRG2.

Research Area: Membrane

Tested Application: E, WB

Application: GABRG2 antibody can be used for detection of GABRG2 by ELISA at 1:62500. GABRG2 antibody can be used for detection of GABRG2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 36 kDa, 54 kDa, 55 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein A chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store GABRG2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: GABRG2, CAE2, ECA2, GEFSP3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Gamma-aminobutyric acid (GABA) , the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA (A) subunits. GABRG2 is the gamma 2 subunit of GABA (A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures.Gamma-aminobutyric acid (GABA) , the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA (A) subunits. This gene encodes the gamma 2 subunit of GABA (A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures. Alternative splicing of this gene results in transcript variants encoding different isoforms.