GAD2 Polyclonal Antibody | E-AB-15661

GAD2 Polyclonal Antibody | E-AB-15661 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 65 kDa glutamic acid decarboxylase, DCE 2, DCE2, DCE2, GAD 2, GAD 65, GAD-2, GAD-65, Gad2, Glutamate decarboxylase 2 (pancreas), Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa), Glutamate decarboxylase 2, Glutamate Decarboxylase 65, Glutamate decarboxylase 65 kDa isoform, Glutamic Acid Decarboxylase 2, Glutamic Acid Decarboxylase 65, MGC161605, MGC161607

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Neuroscience

Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human GAD2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A