GalNAc-T16, soluble fragment, Human Recombinant | P1218

Polypeptide N-acetylgalactosaminyltransferase 16 (GalNAc-T16) catalyzes the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the hydroxyl group of serine and threonine residues. Twenty GalNAc-T genes have been identified in humans and most have been shown to represent active GalNAc-Ts. All isoforms are type II transmembrane proteins, with different but partly overlapping substrate preferences. The GalNAc-Ts control the initiation of mucin-type O-linked glycosylation and determine the location and density of O-glycans in a protein. Addition of GalNAc to an unglycosylated Ser/Thr residue creates the Tn antigen GalNAc1-S/T, and subsequent addition of sialic acid by ST6GalNAc-I forms the cancer associated STn antigen.

P1218 | GalNAc-T16 soluble fragment Human Recombinant DataSheet

Biomolecule/Target: GALNT16

Synonyms: Polypeptide N-acetylgalactosaminyltransferase, Protein-UDP acetylgalactosaminyltransferase, GALNTL1, GALNT16

Alternates names: Polypeptide N-acetylgalactosaminyltransferase, Protein-UDP acetylgalactosaminyltransferase, GALNTL1, GALNT16

Taglines: Involved in the pathway protein glycosylation

NCBI Gene ID #: 14180

NCBI Gene Symbol: FGF-9

Gene Source: Human

Accession #: P54130

Recombinant: Yes

Source: Insect cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: N/A

Concentration: 100 ug/ml

Appearance: Liquid

Physical form description: Sterile filtered solution in 25 mM Tris pH 7.5 and 150 mM NaCl

Reconstitution Instructions: N/A

Amino acid sequence: N/A