Ganoderic Acid A | B3266

Ganoderic Acid is a triterpene found in Ganoderma mushrooms, commonly used in Traditional Chinese Medicine. Ganoderic Acid is reported to display anti-tumor activity mediated through its inhibitory effect on NFKB and AP-1 as well as antimetastasis and anti-HIV activities. It reduces cell viability, expression of superoxide dismutase 1 (SOD1), SOD2, and SOD3, and production of reactive oxygen species (ROS) in PC3 prostate cancer cells. Ganoderic acid A also acts as an inhibitor of the JAK-STAT3 signaling pathway.

Ganoderic Acid is a triterpene found in Ganoderma mushrooms, commonly used in Traditional Chinese Medicine. Ganoderic Acid is reported to display anti-tumor activity mediated through its inhibitory effect on NFKB and AP-1 as well as antimetastasis and ant

B3266 | Ganoderic Acid A DataSheet

Alternate Name/Synonyms: (25R)-7β,15α-dihydroxy-3,11,23-trioxo-lanost-8-en-26-oic acid

Appearance: Solid

Formulation:

CAS Number: 81907-62-2

Structure Available?: Yes

Peptide sequence:

Salt Form: No

Molecular Formula: C₃₀H₄₄O₇

Molecular Weight: 516.67

Cell-Permeable?: True

Purity: ≥95%

Solubilities: ~ 1 mg/ml DMSO, ~3 mg/ml Ethanol

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A biologically active triterpene

MDL Number:

PubChem CID: 471002

SMILES: O=C1CC[C@@]2(C)[C@](C[C@H](O)C([C@@]([C@@H](O)C[C@]3([H])[C@H](C)CC(C[C@@H](C)C(O)=O)=O)(C)[C@]3(C)C4)=C2C4=O)([H])C1(C)C

InChi: InChI=1S/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21,23,32,35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,23+,28+,29-,30+/m1/s1

InChi Key: DYOKDAQBNHPJFD-JNTBEZBXSA-N