GAS6 Antibody (Center) [ApR04999G]

GAS6 Antibody (Center) [ApR04999G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, Rat

Specificity: This GAS6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 242-275 amino acids from the Central region of human GAS6.

Cellular Localisation: Secreted.

Molecular Weight: 74925

Clone: Polyclonal

Gene Name: GAS6 (HGNC:4168)

Gene ID: 2621

Function: Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Summary: Tissue Location: Plasma. Isoform 1 and isoform 2 are widely expressed, isoform 1 being expressed at higher levels than isoform 2 in most tissues. Isoform 2 is the predominant form in spleen

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Growth arrest-specific protein 6, GAS-6, AXL receptor tyrosine kinase ligand, GAS6, AXLLG