GATA3 (Phospho-S308) polyclonal Antibody | BS94017

GATA3 (Phospho-S308) polyclonal Antibody | BS94017 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC IP

Application Range: WB:1:1,000-1:2,000 IHC:1:50-1:200

Background: GATA-3 Antibody (GATA binding protein 3) is a member of the GATA family of transcription factors. GATA-3 appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 has a strong association with estrogen receptor-alpha expression in breast cancer and evidence exists that GATA-3 may be used to predict response to hormonal therapy of breast cancer patients. GATA-3 has also been shown to be a novel marker for bladder cancer. In one study, GATA-3 stained 67% of 308 urothelial carcinomas but no prostate or renal carcinomas.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: GATA3 (Phospho-S308) polyclonal Antibody detects endogenous levels of GATA3 protein only when phosphorylated at S308.

Molecular Weight: 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GATA3, GATA 3, GATA binding factor 3, GATA binding protein 3, GATA-binding factor 3, Gata3, GATA3, HDR, HDRS, MGC2346, MGC5199, MGC5445, Trans acting T cell specific transcription factor GATA 3, Trans-acting T-cell-specific transcription factor GATA-3,

Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser308 of human GATA3.

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: ProA affinity purified

Pathway: