GBGT1 Antibody (Center) [AMM04721G]

GBGT1 Antibody (Center) [AMM04721G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GBGT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 154-185 amino acids from the Central region of human GBGT1.

Cellular Localisation: Golgi apparatus membrane; Single- pass type II membrane protein

Molecular Weight: 40127

Clone: Polyclonal

Gene Name: GBGT1 (HGNC:20460)

Gene ID: 26301

Function: Has lost the ability to synthesize Forssman glycolipid antigen (FORS1/FG) (PubMed:10506200) . Might have acquired an alternative function in glycosphingolipid metabolism, but it remains to be established. It appears to have drifted more slowly than confirmed pseudogenes in the glycosyltransferase 6 family, suggesting that it has remained under evolutionary pressure.

Summary: Tissue Location: Widely expressed. Expressed at higher level in placenta, ovary and peripheral blood leukocyte, whereas it is weakly expressed in liver, thymus, and testis (PubMed:10506200) . Expressed in bone marrow erythroid cells (PubMed:23255552)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Globoside alpha-1, 3-N-acetylgalactosaminyltransferase 1, 2.4.1.-, Forssman glycolipid synthase-like protein, GBGT1