GBP5 Antibody | 7327

GBP5 Antibody | 7327 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: GBP5 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GBP5 .
The immunogen is located within the last 50 amino acids of GBP5.

Research Area: Innate Immunity

Tested Application: E, WB, IHC-P, IF

Application: GBP5 Antibody can be used for detection of GBP5 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: GBP5 antibody is predicted to not cross-react with other GBP family members.

Positive Control 1: Cat. No. 1464 - Rat Liver Tissue Lysate

Positive Control 2: Cat. No. 10-201 - Human Liver Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 64 kDa
Observed: 66 kDa

Validation: N/A

Isoform: N/A

Purification: GBP5 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: GBP5 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: GBP5 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: GBP5 Antibody: GBP-5, Guanylate-binding protein 5, GBP-TA antigen, GBP-5

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: GBP5 Antibody: The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) . GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.