GCAT Polyclonal Antibody | E-AB-18831

GCAT Polyclonal Antibody | E-AB-18831 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 2 amino 3 ketobutyrate CoA ligase , 2 amino 3 ketobutyrate coenzyme A ligase, mitochondrial, 2-amino-3-ketobutyrate coenzyme A ligase, AKB ligase, Aminoacetone synthase, GCAT, Glycine acetyltransferase, glycine C acetyltransferase , glycine C acetyltransferase (2 amino 3 ketobutyrate coenzyme A ligase), KBL, KLB, mitochondrial

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal transduction

Background: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.

Concentration: 1.02 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human GCAT

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 45 kDa

Molecular Weight(Observed): Refer to figures