GCHFR Antibody (C-term) [APR10879G]

GCHFR Antibody (C-term) [APR10879G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GCHFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-66 amino acids from the C-terminal region of human GCHFR.

Cellular Localisation: Nucleus. Nucleus membrane. Cytoplasm, cytosol

Molecular Weight: 9698

Clone: Polyclonal

Gene Name: GCHFR

Gene ID: 2644

Function: Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.

Summary: Tissue Location: In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: GTP cyclohydrolase 1 feedback regulatory protein, GFRP, GTP cyclohydrolase I feedback regulatory protein, p35, GCHFR, GFRP