GCLC monoclonal Antibody | MB63392

GCLC monoclonal Antibody | MB63392 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:200~1000, IHC 1:150

Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. [provided by RefSeq, Oct

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: glutamate-cysteine ligase catalytic subunit

Molecular Weight: 72.6 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GCL; GCS; GLCL; GLCLC

Immunogen: Full length human recombinant protein of human GCLC (NP_001489) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A