GDF-15, Human Recombinant | 4569

Growth and differentiation factor 15 (GDF-15) is a TGF family member, made by in the placenta and heart tissues, that has a role in regulating inflammatory and apoptotic pathways. GDF-15 has become an immerging marker of early heart disease and has the potential as being used as a molecule for screening patients for early heart failure. Recombinant human GDF-15 is a non-glycosylated, disulfide linked homodimer. It is comprised of two identical 120 amino acid monomers and has a total molecular mass of 26.8 kDa.

4569 | GDF-15 human recombinant DataSheet

Biomolecule/Target: GDF-15

Synonyms: MIC1, PDF, PLAB, PTGFB

Alternates names: APOA1, MGC117399, Apoa1, Alp-1, Apoa-1, Brp-14, Ltw-1, Lvtw-1, apolipoprotein, apolipoproteins, MGC102525, Sep-1, Sep-2, Sep2, rat ApoA-1, ApoA-1, ApoA1, Apo A1, r-ApoA-1, rr-ApoA-1, recombinant rat ApoA-1, ApoA1, recombinant ApoA-1, ApoA1, Apolipoprotein A-I, Apolipoprotein AI, Apolipoprotein

Taglines: A protein with functions in regulating inflammatory and apoptotic pathways

NCBI Gene ID #: 25081

NCBI Gene Symbol: Apoa-I

Gene Source: Human

Accession #: NP_036870

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: Endotoxin level as measured by LAL analysis is 1 EU/µg.

Activity (Specifications/test method): N/A

Biological activity:

Results: 1-2 µg/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 27.4 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Recombinant human GDF-15 is lyophilized from a sterile 0.2 micron filtered aqueous solution containing 0.1% trifluoroacetic acid (TFA).

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A